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Image Search Results
Journal: Microorganisms
Article Title: Titanium Wear Particles Exacerbate S. epidermidis -Induced Implant-Related Osteolysis and Decrease Efficacy of Antibiotic Therapy
doi: 10.3390/microorganisms9091945
Figure Lengend Snippet: MicroCT revealed increased S. epidermidis -induced osteolysis in the presence of WPs. A sterile or S. epidermidis -colonized screw was inserted in the unicortical hole created in the proximal tibia of female Wistar rats. Further subgroups included animals receiving 2 mg of sterilized titanium WPs into the screw hole and, in animals receiving the S. epidermidis -colonized screws, a combination antibiotic regimen (+ABs) was administered on days 7–21, followed by a 7-day washout period. The evolution of bone structure was assessed by in vivo microCT imaging at day 0, 6, 9, 14, 20 and 28. n = 6 per experimental group. Asterisks highlight osteolysis around the screw, arrows represent thickening of periosteal regions in proximity of the screw, and white arrows (diamond-headed arrow) represent WPs. Scale bar = 1 mm.
Article Snippet: The evolution of bone structure was assessed using time-lapsed in
Techniques: Sterility, In Vivo, Imaging